administering medicines to children. It has been prepared under the guidance of the Paediatric. Formulary Committee. BNF for Children has been constructed. Material published in the BNF for Children (BNFC) may not be used for any form of ryaleomitsuvi.cf Prescriptions. Free online access to the UK BNFc (British National Formulary for Children) content published by NICE - last updated 2 April
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PDF | On Feb 1, , J Kowalczuk and others published British National Formulary for Children (BNFC). Description. The BNF for Children (BNFC) provides essential practical information to all healthcare professionals involved in the prescribing. The BNF & BNF for Children app for Android. The app contains content from both BNF and BNF for Children. Both of these formularies are organised.
This committee would consider whether studies are likely to show therapeutic benefit and would be expected to turn down those it thought would unnecessarily duplicate other work, while not delaying authorisation of medicines for other ages.
In addition the European Medicines Agency has issued a draft guideline on pharmacovigilance among children. This empowers the Food and Drug Administration FDA to require manufacturers to test medicines for safety and effectiveness in children and to establish protocols for paediatric dosing and administration. The FDA can waive such requirements when a drug is unlikely to be used in children and can defer decisions on paediatric prescribing when a drug needs urgent authorisation for adult use.
The BNF for Children has been validated against emerging evidence, guidelines on best practice, and advice from a network of clinical experts. An online version for England is almost ready. References 1. Hill P.
Off license and off label prescribing in children: litigation fears for physicians. Arch Dis Child ; Survey of unlicensed and off label drug use in paediatric wards in European countries.
BMJ ; Unlicensed and off label prescribing of drugs in general practice. Off label and unlicensed drug use among French office based paediatricians. Unlicensed and off label prescription of drugs to children: population based cohort study. Unlicensed and off-label drug use in an Australian neonatal intensive care unit. Pediatrics ; e The impact of unlicensed and off-label drug use on adverse drug reactions in paediatric patients.
Drug Safety ; Users can access any section, such as indication and dose, with a single tap. Searching for a specific drug is performed in the monographs section — either by typing in the drug name or by browsing an alphabetical list of drug monographs.
Treatment summaries provide a concise summary of a therapeutic area and can be accessed by typing the name of a condition into the search field or by browsing alphabetically within body systems e.
Treatment summaries are subdivided into sections, including aims of treatment, drug treatment and non-drug treatment.
The summaries contain links to individual drug monographs, allowing the user to direct their attention to drug-specific information such as doses, side-effects and the preparations available see Figure 1: Treatment summary example.
Show Fullscreen Figure 1: Understanding the new interface of the BNF and BNFC app Sample images were obtained using an iOS device One of the objectives of the new app is to enhance user experience and allow quicker and easier access to drug information. On an iOS screen, the menu is located at the bottom pictured , while Android users have to swipe to access it C Drug monograph: Information is divided into the same sections as used in the print and online versions.
Each section can be viewed with a single tap. Searching is also performed in the monograph section D Treatment summary example: Searching for a particular drug will also generate all of the BNF content relevant to that drug, including discussions of its use There are separate sections for borderline substances, medical devices and wound care, where products are displayed according to their uses, making them easy to find and select.
Box 1 provides more information on how the evidence grading function can be applied to the content displayed through the app. Box 1: Evidence grading Recommendations made in BNF publications have been evidence graded to reflect the strength of the recommendation since January Evidence grading has been applied in order to support clinical decision-making based on the best available evidence. The option to turn evidence categories on and off can be found here B.
When this is turned on, the evidence grades assigned to recommendations are displayed clearly within the content C. More evidence-graded content will be available with each monthly update, until all recommendations made within the app content are graded. Box 2: How to use the BNF app in clinical practice using a case study A year-old patient comes into your pharmacy with a prescription for sildenafil 50mg tablets for erectile dysfunction ED , to be used when required.
He tells you he has not used sildenafil before and will come back in half an hour to pick it up. He has no known allergies to medication and has no other pending treatment or investigations. Case discussion: Before dispensing, how can you check the prescribed dose is suitable using the BNF app?
You see that 50mg is a suitable dose for ED, to be taken 1 hour before sexual activity 2. By going back to the menu pane, you can check all of the other sections in this monograph and read the other relevant sections for further information on cautions, contra-indications and prescribing in hepatic and renal impairment 3.
You are also able to check all of the medicinal forms that are available to dispense to the patient, as well as checking the NHS price. You choose the interactions checker from the menu pane, enter all four drugs — cimetidine, aspirin, atorvastatin and sildenafil — into the search field 4. This search brings up all the relevant interactions.
You see that cimetidine increases the plasma concentration of sildenafil, and the recommended dose the patient uses is 25mg to begin with 5. Show Fullscreen When the patient returns to collect their medication, what other advice can you offer him?
You tell the patient that they should take their medication one hour before sexual activity and explain some common side effects using the information in the side effects section. You explain that there is a potential drug interaction and suggest that he starts on 25mg because of this, with the option to increase this to 50mg.
Show Fullscreen The patient has listened carefully to the information but now has questions about what has caused the ED.